Tricarboxylic acids and derivatives
Apexbio Technology LLC Citrate-Synthase-Act-Assay-Kit
Citrate Synthase Activity Assay Kit is a crucial tool in biochemical and pharmaceutical research primarily used to measure the enzymatic activity of citrate synthase an essential enzyme in the citric acid cycle Originating from cellular metabolism studies it aids in understanding the conversion of oxaloacetate and acetyl-CoA to citrate and CoA-SH This reaction plays a pivotal role in energy production and metabolic regulation The kit is commonly used in in vitro assays with activity detectable in nanomolar to low micromolar ranges Applications include use in cellular models animal studies and drug screening to analyze metabolic pathways and potential drug interactions Experimental concentrations typically depend on the specific research design Its precision and reliability make it indispensable for academics and industry professionals investigating metabolic disorders cancer metabolism and mitochondrial function
Medchemexpress LLC Amino-PEG5-CH2COOH | 141282-35-1 | ≥97.0% | 500 MG
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets the protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Targets PROTAC linkers within the PROTAC pathway
- Solid appearance
- White to off-white color
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
Medchemexpress LLC Triammonium phosphate trihydrate | 25447-33-0 | MFCD00151223 | ≥98.0% | 203.13 | H18N3O7P | 1kg
Triammonium phosphate trihydrate interacts with the magnesium ions to form a precipitate which can be used for magnesium separation from lithium in salt-lake brines[1]
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | 50 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These PROTACs feature two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other binds to a specific target protein. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Leverages ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Triammonium phosphate trihydrate | 25447-33-0 | MFCD00151223 | ≥98.0% | 203.13 | H18N3O7P | 500g
Triammonium phosphate trihydrate interacts with the magnesium ions to form a precipitate which can be used for magnesium separation from lithium in salt-lake brines[1]
Medchemexpress LLC Oxeladin citrate | 52432-72-1 | 98.0% | 1 ML
Oxeladin citrate is an orally active and brain-penetrant cough suppressant. It acts as a selective sigma 1 receptor agonist with a Ki of 25 nM, and has potential applications in pulmonary diseases and stroke research.
- Orally active and brain-penetrant cough suppressant
- Selective sigma 1 receptor agonist
- Used for pulmonary diseases and stroke research
- Facilitates S1R mediated brain-derived neurotrophic factor secretion
- Reduces infarct expansion in subacute phase of stroke
- Improves neurological function
Apexbio Technology LLC trans-Aconitic acid 4023-65-8 5g
trans-Aconitic acid (CAS 4023-65-8) is an unsaturated tricarboxylic acid endogenously detected in human urine It serves as a substrate for trans-aconitate 2-methyltransferase implicating it in metabolic pathways related to citrate metabolism Elevated urinary levels of trans-aconitic acid have been observed in conditions such as Reye s syndrome and certain organic acidurias suggesting its potential as a metabolic biomarker This compound is utilized in biomedical research to investigate metabolic dysregulation and to study enzyme-substrate interactions within organic acid metabolism
Medchemexpress LLC Fmoc-NH-PEG1-CH2COOH | 260367-12-2 | MFCD06796876 | 99.9% | 341.36 g·mol⁻¹ | C19H19NO5 | 25 G
Fmoc-NH-PEG1-CH2COOH is an Fmoc-protected PEG1 linker bearing a terminal carboxylic acid used as a cleavable linker in antibody-drug conjugate (ADC) synthesis and as a PEG-based PROTAC linker in conjugation chemistry. It has CAS number 260367-12-2, molecular formula C19H19NO5, and a molecular weight of 341.36 g·mol⁻¹.
- Cleavable ADC linker for antibody-drug conjugation.
- Suitable as a PEG-based PROTAC linker.
- Fmoc-protected amine enables standard peptide and solid-phase chemistries.
- High reported purity suitable for synthetic applications.
- Available in multiple pack sizes including 25 G for preparative work.